The Manual of Diagnostic Tests and Vaccines for Terrestrial Animals from the World Organisation for Animal Health (WOAH) was created to prevent the spread of animal and zoonotic diseases by providing internationally agreed upon standards and methods for animal vaccinations and veterinary diagnostic laboratories. The manual covers infectious and parasitic diseases in mammals, birds and bees, and is divided into four parts: 1. General standards for management of diagnostics laboratories and vaccine production facilities, 2. Specific recommendations on validation of diagnostic tests and the manufacture of vaccines, 3. WOAH listed diseases and other important diseases, 4. WOAH Reference Centers at the time of publication.

The Terrestrial Manual is a companion volume to the Terrestrial Animal Health Code, and has been foundational to the animal health field since its first publication in 1989. The Manual is updated regularly. As of 2022 the Manual is no longer available in printed format, and must be accessed online. The 12th edition was published in 2023 and is available in English, French, and Spanish on the WOAH site.

WOAH was established in 1924, has 182 member countries and is a leading global authority on animal health. WOAH receives its mandate from the World Trade Organization (WTO) Agreement on Sanitary and Phytosanitary Measures, and this manual helps safeguard world trade by maintaining animal vaccine and disease testing standards.