By achieving a delicate balance between systems and practices, proper laboratory biosecurity reduces the risk of legitimate bioscience facilities becoming sources of pathogens and toxins for malicious use. Effective design and implementation of laboratory biosecurity depends on cooperation among individuals from diverse communities, including scientists, technicians, policy makers, security engineers, and law enforcement officials. Providing guidance to the broad international community, Laboratory Biosecurity Handbook addresses the objectives of biosecurity and the ways in which they overlap or conflict with those of biosafety. Addressing a variety of operating environments and the particular challenges they face when designing and implementing laboratory biosecurity, this book can assist bioscience facilities ranging from the large to the small, from those that focus on diagnosis or vaccine development, to those only minimally involved with infectious diseases. The detailed recommendations help avoid a "one-size-fits-all" approach to security and save limited resources. The book shows institutions how to develop and implement a biosecurity plan, and helps ensure that all components are included in the overall system, whether existing or new. The book includes questionnaires that can assist the process of collecting data for a biosecurity vulnerability assessment, example standard operating procedures and memoranda of understanding, and other useful reference material.

The book was published by Sandia National Laboratories in 2007. Sandia National Laboratories is a defense research contractor for the United States government that is owned by a private company. The book was edited by Reynolds Salerno, a senior manager for Biological Sciences and Technologies at Sandia, and Jennifer Gaudioso, the Director of the Computation and Analysis for the National Security Center at Sandia, and is available in English. The book must be purchased to access.